Fig. 1

Multi-omic measures from the NASA Twins study. Work from the NASA Twins Investigators Group established a first draft multi-omics profiling and data integration framework that included data from the genome (DNA), epigenome (modified DNA and chromatin states), transcriptome (RNA), epitranscriptome (modified RNAs), proteome (LC-MS), metabolome (GC-MS), antibody profiling and VDJ recombination, B-cell/T-cell counts and sequencing, telomere length (FISH, ddPCR), cytokine measures, targeted and global metabolomics, microbiome and metagenome, cognition, and vasculature dynamics