Fig. 2
From: GRIPT: a novel case-control analysis method for Mendelian disease gene discovery
The example of gene score distribution. This figure shows the gene score distributions of USH2A in a retinal disease cohort of 250 patients (in red) and in a control cohort of 250 individuals (in blue). X axis: the gene score of USH2A per individual. Y axis: the numbers of patients or controls with the corresponding score. Like the gene USH2A, the gene score distributions of most genes are highly skewed with excesses of zeros