Fig. 3From: Phytophthora methylomes are modulated by 6mA methyltransferases and associated with adaptive genome regionsBimodal distribution pattern of 6mA around TSS in Phytophthora. The distribution of 6mA peaks around TSS was profiled by MeDIP-seq. The 6mA occupancy along TSS from − 2 to 2 kb is shown. 6mA peaks were enriched around TSS with a bimodal distribution and a local depletion after TSS in P. infestans and P. sojae. a 6mA occupancy in P. infestans methylated genes. All P. infestans genes are divided into 6mA methylated genes (n = 1805) and non-6mA methylated genes (n = 16374). b 6mA occupancy in P. sojae methylated genes. All P. sojae genes are divided into 6mA methylated genes (n = 1343) and non-6mA methylated genes (n = 17853). c Heatmap analyses of 6mA signal from individual genes verified the bimodal distribution pattern in both Phytophthora species. The relative methylation signal is represented using gradient colors. d The 6mA level is negatively correlated with gene expression in P. infestans. All genes are divided into two groups: high expression (FPKM ≧ 5, n = 9927) and low expression (FPKM < 5, n = 8252). e The 6mA level is negatively correlated with gene expression in P. sojae. All genes are divided into two groups: high expression (FPKM ≧ 5, n = 9450) and low expression (FPKM < 5, n = 9746)Back to article page