Fig. 5
From: Genetic disease risks can be misestimated across global populations
GWAS simulations reveal that continental differences in allele frequencies persist even if whole genome sequencing and large sample sizes are used. Bean plots show the results of 1000 simulations per set of parameter values (3036 disease associations per simulation). Simulations using SNPs on genotyping arrays are represented by light shading, and simulations using WGS data are represented by dark shading. Colors indicate whether risk alleles are ancestral (red) or derived (blue). Sample sizes shown are the number of cases and the number of controls