Fig. 2

Induction times of transcription, Pol2 binding, and histone modifications at promoters in function of induction of transcriptional activation times. a Heatmap showing the changes (white, no change; red, induction; blue, repression) in transcriptional activity of 1413 LPS-induced promoters and stably expressed promoters, relative to time point 0 h. At the right, induction times and the number of promoters induced at each time point are indicated. b–g Timing of increases in RNA-seq reads (b), Pol2 binding (c), H3K27ac (d), H3K9K14ac (e), H3K4me3 (f), and H3K36me3 (g) at LPS-induced promoters is shown in function of their transcription initiation times. The count of promoters with increases is indicated. Note that the sum of the counts differs between each panel. Colors represent the fraction of promoters per transcriptional induction time