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Table 1 Descriptive summary of population samples

From: Interaction between the microbiome and TP53 in human lung cancer

 

Control lung

 

NCI-MD study

 

TCGA study

 

ImA

HBa

Normal adjacent

Tumor

Normal adjacent

Tumor

(n = 33)

(n = 16)

(n = 144)

(n = 143)

(n = 108)

(n = 974)

Age - mean (SD)

39.5 (18.8)

62.6 (7.7)

65.5 (9.8)

65.7 (9.9)

66.9 (9.9)

66.4 (9.2)

  < Mean

18

9

70

63

49

396

  ≥ Mean

15

7

74

80

59

578

 Unknown

    

5

128

Gender

 M

25

11

92

87

58

514

 F

8

5

52

56

45

355

 Unknown

    

5

105

Raceb

 EA

27

14

86

95

90

650

 AA

5

2

58

48

8

42

 Other

     

59

 Unknown

1

   

10

223

Smoking statusb

 Ever

 

14

122

127

90

768

 Former

 

11

44

40

71

551

 Current

 

3

64

70

19

217

 Never

 

2

9

7

7

120

 Unknown

      

Stage

 I (a/b)

   

69

52

454

 II (a/b)

   

44

28

231

 III (a/b)

   

11

19

155

 IV

   

2

3

29

 Unknown

   

16

6

105

Histology

 AD

   

67

58

485

 SCC

   

47

50

489

 Other

   

29

  

TP53 mutation status

 Wild-type (AD/SCC)

   

32/11

 

125/59

 Mutant (AD/SCC)

   

29/35

 

104/118

 Unknown

   

36

 

568

  1. aTwo cases removed due to emphysema
  2. bSmoking status and race self-reported
  3. ImA immediate autopsy, HB hospital biopsy