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Fig. 3 | Genome Biology

Fig. 3

From: DNA Topoisomerase I differentially modulates R-loops across the human genome

Fig. 3

R-loop signal at RLG genes are co-transcriptional. a Distribution of all peaks of R-loop gain and loss (p-adjusted < 0.1) along a gene metaplot, normalized by number of genes in each length category. Genes are broken down by length, as indicated at top. Genes were binned in 40 bins and peak counts reported by bin. bc Metaplots of DRIPc-seq signal over RLG genes (b) and RLL genes (c) along a 20 kilobase window centered on their TSS at left, or PAS at right. Values are median and shown with standard deviation (shaded). Samples are color-coded as indicated

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