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Fig. 6 | Genome Biology

Fig. 6

From: OCEAN-C: mapping hubs of open chromatin interactions across the genome reveals gene regulatory networks

Fig. 6

Overlaps between HOCIs and super-enhancers. a Identification of super-enhancers in U266 cells based on E2F1 or DP1 signals. b Venn diagram showing the overlap between the two types of super-enhancers defined by E2F1 or DP1 signals (U266). c The length distribution of the two types of super-enhancers defined by E2F1 or DP1 signals (U266). SE super-enhancer. d Proportions of super-enhancers overlapping HOCIs. e Venn diagram showing the overlap between super-enhancers and HOCIs. The p values were generated using Fisher test. f The browser view of a genomic region in chromosome 14, showing HOCI-mediated chromatin interactions within and between super-enhancers (GM12878). OCEAN-C interaction: both ends of OCEAN-C read pairs mapped to HOCIs. Pink, interactions between super-enhancer-related enhancer HOCIs; gray, all interactions

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Genome Biology

ISSN: 1474-760X

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