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Fig. 7 | Genome Biology

Fig. 7

From: PureCLIP: capturing target-specific protein–RNA interaction footprints from single-nucleotide CLIP-seq data

Fig. 7

Summary of the hidden Markov model framework. a Starting from mapped reads (bottom), observations are deduced (individual read start counts, which are further smoothed to obtain pulled-down fragment densities) and combined with additional covariates (top) to reconstruct the most likely sequence of hidden states (middle). b Graphical representation of the corresponding non-homogeneous hidden Markov model. CL crosslink-associated

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