Experimental design and quantitative analysis of microbial community multiomics

Table 4 Tools for compositionality-aware ecological network inference

Tool	Infers directed interaction?	Adjusts for covariates?	Reference(s)
CCREPE/ReBoot	No	No	[64]
SparCC	No	No	[65]
CCLasso	No	No	[66]
REBACCA	No	No	[139]
SPIEC-EASI	No	No	[67]
MENAP	No	No	[140]
MInt	No	Yes	[141]
MetaMIS	Yes	No	[142]
BioMiCo/BiomeNet	Yes	No	[143, 144]
MDSINE	Yes	No	[87]
DBN	Yes	No	[145]

ISSN: 1474-760X