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Fig. 6 | Genome Biology

Fig. 6

From: BayFish: Bayesian inference of transcription dynamics from population snapshots of single-molecule RNA FISH in single cells

Fig. 6

Bayesian posterior distribution for (k 1,k 0)-stimulus model run on Npas4 smFISH data. a Marginal posterior distributions of parameters for BayFish replicas (i.e., different colors correspond to distinct random number generator seeds and initial conditions). There are two distributions for k 0 and k 1, one of which is the pre-stimulus parameter (continuous lines) and the other is the post-stimulus parameter (dotted lines). b The mean distribution of mRNA and active transcription site 〈P(X,τ)〉 as inferred from the Bayesian posterior distribution of parameters. The standard deviation (σ P ) is shown in gray. A histogram of experimental data is shown for comparison (green dots)

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