Table 1 List of selected GWAS SNPs that are linked to both edQTL and ASED SNPs
From: Population and allelic variation of A-to-I RNA editing in human transcriptomes
Gene symbol | Editing site | ASED SNP | edQTL SNP | Linked GWAS SNP(s) | GWAS gene symbol | GWAS disease/trait | Reference (PMID) |
|---|---|---|---|---|---|---|---|
PSPH | Chr7:56078339 | NA | rs4947534 | rs4947534 | PSPH | Blood metabolite levels | 24816252 [73] |
Chr7:56079087 | rs4947534 | NA | |||||
Chr7:56079100 | rs4947534 | NA | |||||
ATM | Chr11:108236635 | NA | rs12801988 rs227080 rs170546 rs5023001 | rs11212617 | C11orf65 | Response to metformin in type 2 diabetes (glycemic) | 21186350 [42] |
Chr11:108237818 | rs227091 | NA | |||||
Chr11:108237819 | rs227091 | NA | |||||
Chr11:108237832 | rs227091 | rs227080 rs227090 | |||||
Chr11:108237844 | rs227091 | NA | |||||
Chr11:108237854 | rs227091 | NA | |||||
ICOSLG | Chr21:45644472 | rs8127114 | rs8127114 | rs4819388 | ICOSLG | Celiac disease | 20190752 [74] |
GINS1 | Chr20:25427805 | rs6037121 rs6050623 | NA | rs7267979 | ABHD12 | Liver enzyme levels (alkaline phosphatase) | 22001757 [75] |
Chr20:25427815 | rs6050626 rs6050623 | rs2258728 | |||||
Chr20:25428294 | rs1047171 rs6050626 rs6037121 | NA | |||||
Chr20:25428308 | rs6050626 | NA | |||||
Chr20:25428320 | rs6050626 rs6050623 | NA | |||||
Chr20:25428646 | rs1047171 | NA | |||||
Chr20:25428669 | rs1047171 | NA | |||||
Chr20:25428724 | rs1047171 | NA | |||||
Chr20:25428750 | rs6037121 | NA | |||||
CCL28 | Chr5:43380817 | NA | rs7706402 | rs11951515 | CCL28 | Metabolite levels (X-11787) | 23934736 [76] |
Chr5:43381564 | rs7706402 | NA | |||||
FAM129A | Chr1:184761188 | rs492126 rs682331 | rs570441 rs682331 | rs682331 | FAM129A | Obesity-related traits | 23251661 [77] |
Chr1:184762487 | rs526024 | NA | |||||
Chr1:184762590 | rs492126 | NA |