Fig. 1
From: Revisit linear regression-based deconvolution methods for tumor gene expression data
Simulations showing negative associations in CIBERSORT estimates. a, b CIBERSORT reported a negative correlation between unrelated features, CD8 T cells and neutrophils. The fractions of features were independently sampled from Uniform(0,0.5). c, d CIBERSORT reported a stronger negative association between closely correlated features, naïve and memory B cells; the sampling procedure used in a, b was applied. Simulated data were sent to the CIBERSORT online server using LM22 as a reference matrix and default parameters