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Table 1 Selected non-synonymous mutations identified by the C580Y-like and C580-vector-like temporal analyses and GWAS

From: Longitudinal genomic surveillance of Plasmodium falciparum malaria parasites reveals complex genomic architecture of emerging artemisinin resistance

Gene annotation Gene ID Chromosome Amino acid change Method
Phosphatidylinositol 4-kinase, putative PF3D7_0419900 4 S915G C580Y-like
Sec14 domain-containing protein PF3D7_0626400 6 L498F
Ubiquitin-protein ligase, putative (Hrd3) PF3D7_1448400 14 S57T C580Y-like
Ubiquitin carboxyl-terminal hydrolase, putative PF3D7_0104300 1 R3138H C580Y-like
HSP40, subfamily A, putative PF3D7_1437900 14 P383H C580Y-vector-like
Sentrin-specific protease 2, putative (SENP2) PF3D7_0801700 8 H423Y C580Y-like
kelch protein, putative PF3D7_1022600 10 P623T GWAS (mutant kelch13)
kelch protein, putative PF3D7_1343700 13 C580Y GWAS (all samples)