Fig. 4

RNA binding proteins (RNAbps) modulate IR. a RNAbp motifs enriched (Z score >1.96) in frequently retained introns (5′ and 3′ intron boundaries) and flanking exons. No depleted motifs were found. b Number of increased and decreased IR events at different p values of significance following knockdown (KD). Total numbers of increased and decreased IR events are indicated on the plot. Motif enrichment p values in increased IR events for each RNAbp are displayed below their protein names. c The number of increased IR events compared to the number of retained introns following knockdown for which there was no evidence of retention before knockdown