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Fig. 1 | Genome Biology

Fig. 1

From: IRFinder: assessing the impact of intron retention on mammalian gene expression

Fig. 1

Intron retention is widespread and its measurement is consistent within the same tissue type. a Number of retained introns in each of the 2573 downloaded samples that were retained in more than 10% (red), 20% (green), 30% (blue) of transcripts (IR ratio >0.1, 0.2, 0.3). b Average IR ratio in eight different tissue types. hESC human embryonic stem cell. c Genes with IR events occur closer than expected. Genomic distance between genes with IR events (blue) compared to a control of the same number of randomly selected expressed genes. d Retained introns within the same gene are often adjacent to each other. Number of introns that are separated by only one exon (x-axis) in the same gene (blue) compared to a control where the number of IR events within each gene are randomly distributed amongst introns

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