Fig. 3From: Whole exome sequencing coupled with unbiased functional analysis reveals new Hirschsprung disease genesNewly identified genes in ENS development. All symbols represent proteins coded by genes known to be involved in HSCR or novel genes identified in this study. The effect of NUP98 is shown by protein NUP96. The interaction effects between different proteins are illustrated by four different lines representing binding, secreted/express, phosphorylation, and activation. ENCC enteric neural crest cellBack to article page