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Fig. 2 | Genome Biology

Fig. 2

From: Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23

Fig. 2

Validation of CHi-C results by 3C-qPCR in GM12878 and Jurkat cell lines. The graphs show the relative interaction frequency of (a) the 6q23 intergenic disease SNPs tagged by rs6920220, (b) the TNFAIP3 gene and (c) the IL20RA gene with their respective targets (dark grey) compared to control, non-interacting fragments (C-, light grey). Diagrams below each graph show the approximate location of the primers for the anchor, negative control (C-) and target (★) regions. Error bars indicate standard deviation of three biological replicates; * indicates t-test P value <0.05

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Genome Biology

ISSN: 1474-760X

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