Fig. 3
From: Novel regional age-associated DNA methylation changes within human common disease-associated loci
Fold enrichments for a-DMRs compared to LD block non-overlapped 500-bp windows. All categories are enriched in a-DMRs (χ2 p all < 1 × 10–5) except for transcripts (near identical fraction), SINE and LTR repeats (non-significant) and all repeats and LINE repeats, which are significantly depleted (χ2 p = 6.73 × 10–9 and 2.81 × 10–3, respectively). CGI CpG Islands, TSS transcription start sites, DNase I HSs DNase I hypersensitivity sites in 125 cell types, TFBS transcription factor binding sites, CTCF and Sp1 from all tissues (ENCODE v3), Repeats All, SINE, LINE, LTR repeats, FANTOM5 Enhancers [36], Dynamic Regions [66] and Conserved (100 Vertebrate) regions [87]