Fig. 6From: An expanded evaluation of protein function prediction methods shows an improvement in accuracyOverall evaluation using the minimum semantic distance, S min. Evaluation was carried out on no-knowledge benchmark sequences in the full mode. The coverage of each method is shown within its performance bar. A perfect predictor would be characterized with S min=0. Confidence intervals (95 %) were determined using bootstrapping with 10,000 iterations on the set of benchmark sequences. For cases in which a principal investigator participated in multiple teams, the results of only the best-scoring method are presented. Details for all methods are provided in Additional file 1 Back to article page