Fig. 1
From: Integrating epigenomic data and 3D genomic structure with a new measure of chromatin assortativity
Chromatin assortativity (ChAs) of epigenomic features in a network of chromatin contacts. a Largest connected component of PCHi-C chromatin interaction network in mESCs. Nodes are colored by proportion of fragment covered by EZH2, which highlights the neighborhoods in which the protein is abundant. b The genomic region highlighted in the box in (a) visualized using the WashU Epigenome browser [67] with added custom tracks for PCHi-C interactions and EZH2 peaks together with other PcG-related features. c Cartoon illustrating what ChAs measures. Each node of the network is a chromatin fragment, blue nodes represent nodes in which a peak of a specific chromatin mark is found, and edges represent significant 3D interactions. Next to it we show a cartoon plot of ChAs versus abundance