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Fig. 3 | Genome Biology

Fig. 3

From: CHiCAGO: robust detection of DNA looping interactions in Capture Hi-C data

Fig. 3

Read count distributions in typical CHi-C experiments and fit to the CHiCAGO background model. Histograms showing read count distributions for fragment pairs spanning different distance ranges (±20 kb) in a biological replicate of GM12878 (left) and mESC (right) CHi-C data. Solid lines indicate expected count distributions according to the CHiCAGO background model. The expected distribution was derived by taking samples from the null model, then kernel smoothing the resultant histogram to form a curve for visualisation purposes

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