Fig. 7
Association of RFS with the levels of cytokines and lipid mediators in ovarian carcinoma ascites. a Summary of RFS analyses showing the p values determined by Mantel-Cox log rank test. Patients were dichotomized into high and low expressing groups according to the following quantiles (best-fit) and number or patients: IL-10, Q = 0.66 (n = 36); IL-6, Q = 0.5 (n = 39); TGFβ1, Q = 0.25 (n = 39); AA, Q = 0.25 (n = 38); LTB4, Q = 0.25 (n = 38); PLA2G7, Q = 0.33 (n = 33). Significant instances with a HR >1 are shown in red; grey bars indicate lack of significant associations. Significance was defined as logrank p <0.05 and p < Benjamini-Hochberg critical value for false discovery rate (FDR) = 0.10. b–g Kaplan–Meier plots showing the RFS of patients with high or low ascites levels (best-fit) of IL-10, IL-6, TGFβ1, PLA2G7, AA, and LTB4 (see “Methods” for details)