Table 7 Performance metrics under simulation scenario 5 (low precision)
From: An evaluation of methods correcting for cell-type heterogeneity in DNA methylation studies
Method | Number of false positives | Power | KS | GIF | \(\hat {K}\) |
|---|---|---|---|---|---|
Unadjusted | 127 | 0.622 | 0.241 | 1.47 | – |
Ref-based | 354 | 0.654 | 0.198 | 1.49 | – |
Ref-free | 596 | 0.670 | 0.145 | 1.48 | 12 |
SVA | 123 | 0.644 | 0.091 | 1.23 | 6 |
ISVA | 72 | 0.482 | 0.040 | 1.12 | 11 |
EWASher | 1 | 0.052 | 0.030 | 0.92 | – |
CellCDec | 169 | 0.598 | 0.008 | 1.27 | – |
Deconf | 184 | 0.644 | 0.204 | 1.41 | – |
RUV | 2943 | 0.654 | 0.228 | 1.93 | 33 |