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Table 4 Performance metrics under simulation scenario 2 (no confounding)

From: An evaluation of methods correcting for cell-type heterogeneity in DNA methylation studies

Method Number of false positives Power KS GIF \(\hat {K}\)
Unadjusted 38 0.642 0.059 1.09
Ref-based 13 0.594 0.030 0.90
Ref-free 366 0.704 0.058 1.25 14
SVA 79 0.646 0.015 1.06 10
ISVA 408 0.654 0.061 1.27 15
EWASher 0 0.126 0.066 0.83
CellCDec 14 0.650 0.021 0.93
Deconf 50 0.652 0.031 0.92
RUV 134 0.640 0.007 1.00 38
  1. KS Kolmogorov–Smirnov statistic, GIF genomic inflation factor