Fig. 1
From: Systematic identification of genetic influences on methylation across the human life course
Temporal pattern of mQTL. a The total number of cis and trans mQTL discovered at each time point. b Total bars represent the SNP heritability at each time point. Each bar is split into genetic variation due to common SNPs acting in cis (blue) and trans (green). Cis and trans variation is further divided into the proportion that is explained by mapped SNPs (p < 1 × 10−14). c The proportion of discovered mQTL at a specific time point that replicate at p < 1 × 10−7 in each of the other time points. Darker colours correspond to lower replication rates