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Fig. 3 | Genome Biology

Fig. 3

From: Single-CpG resolution mapping of 5-hydroxymethylcytosine by chemical labeling and exonuclease digestion identifies evolutionarily unconserved CpGs as TET targets

Fig. 3

5hmC detection by SCL-exo in genomic DNA from NPLCs does not depend on CpG density. a Average TET1 ChIP-seq signal in 4000 bp regions around SCL-exo id CpGs sorted according to their CpG density (number of CpGs per 300 bp). b Mean SCL-exo signal at id CpGs sorted according to their surrounding CpG density. c Scatter plot of the SCL-exo signal at id CpGs as a function of CpG density (r: Pearson’s correlation coefficient). d Mean SCL-exo signal at SCL-exo id CpG as a function of CpGs density. e Mean hMeDIP-seq signal at id CpGs sorted according to their surrounding CpG density. f Inclusion of SCL-exo id CpGs in hMeDIP peaks as a function of CpG density

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Genome Biology

ISSN: 1474-760X

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