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Table 9 Comparison of EAGER to a benchmark data set from GIAB

From: EAGER: efficient ancient genome reconstruction

Pipeline

GIAB Sensitivity

GIAB Specificity

GCAT

85.21 %

99.9975 %

EAGER

88.21 %

99.9963 %

PALEOMIX

82.83 %

99.9962 %

  1. GCAT is the result of GCAT using BWA followed by the GATK Unified Genotyper. EAGER is the result that was produced using EAGER and also BWA with standard parameters for the Unified Genotyper of GATK. PALEOMIX is the result that was produced using PALEOMIX using BWA and the SAMtools mpileup method to get genotypes