Fig. 4
From: Quality control, modeling, and visualization of CRISPR screens with MAGeCK-VISPR
The β scores of MAGeCK-MLE on the melanoma knockout dataset. a A k-means clustering view of β scores of all conditions from top selected genes (k = 4). Only genes with the highest or lowest 1 % β scores in DMSO or PLX 14-day treatment conditions are shown. b The distribution of scores across four conditions using different algorithms. The red rectangle in MAGeCK-MLE indicates genes in cluster 4 in Fig. 4a, or genes that are strongly positively selected in PLX 14-day condition. Some validated genes in the original study are marked as red dots, including NF1, NF2, MED12, and CUL3