Skip to main content

Advertisement

Table 3 Top 3 annotation clusters enriched in proestrus versus diestrus common between RNA-sequencing and Chromatin immunoprecipitation-sequencing analyses

From: The estrous cycle surpasses sex differences in regulating the transcriptome in the rat medial prefrontal cortex and reveals an underlying role of early growth response 1

Cluster enrichment score Term Count p-value Fold enrichment
Cluster #1: 2.72 Synapse 14 3.07E−08 7.24
  Cell junction 13 1.27E−06 5.82
  Plasma membrane 29 1.77E−06 2.37
  Plasma membrane part 21 4.06E−06 3.03
  Synapse part 10 4.81E−06 7.56
  Postsynaptic membrane 7 5.92E−05 10.01
  Synaptic transmission 7 5.03E−04 6.78
  Cell-cell signaling 8 7.78E−04 5.14
  Transmission of nerve impulse 7 1.90E−03 5.25
  Exocytosis 5 2.01E−03 9.14
  Postsynaptic density 4 8.24E−03 9.44
  Secretion by cell 5 1.51E−02 5.15
  Neurotransmitter secretion 3 2.41E−02 12.24
  Secretion 5 3.49E−02 3.97
  Vesicle-mediated transport 6 5.15E−02 2.91
  Regulation of neurotransmitter levels 3 5.77E−02 7.58
  Neurotransmitter transport 3 7.82E−02 6.36
  Generation of a signal involved in cell-cell signaling 3 8.78E−02 5.95
  Regulation of cellular localization 4 1.37E−01 3.06
  Protein domain specific binding 4 1.99E−01 2.55
  Regulation of secretion 3 3.14E−01 2.60
  Neurological system process 9 6.40E−01 1.03
Cluster #2: 2.30 Biological adhesion 9 1.23E−03 4.12
  Cell adhesion 9 1.23E−03 4.12
  Cell-cell adhesion 4 8.08E−02 3.87
Cluster #3: 1.74 Postsynaptic membrane 7 5.92E−05 10.01
  Cytoskeleton 11 1.70E−02 2.29
  Cytoskeletal part 9 2.15E−02 2.54
  Intracellular non-membrane-bounded organelle 12 2.99E−01 1.29
  Non-membrane-bounded organelle 12 2.99E−01 1.29