Table 6 Top 20 SEED subsystems for genes identified uniquely by subtractive assembly in the T2D cohort
Rank | SEED subsystem | Number of genes |
|---|---|---|
1 | Peptidoglycan biosynthesis | 635 |
2 | Ton and Tol transport systems | 451 |
3 | Multidrug resistance efflux pumps | 427 |
4 | DNA replication | 424 |
5 | DNA repair, bacterial | 364 |
6 | Cell division subsystem | 345 |
7 | Lactose and galactose uptake and utilization | 322 |
8 | Restriction-modification system | 322 |
9 | Fructooligosaccharides and raffinose utilization | 292 |
10 | Glycerolipid and glycerophospholipid metabolism | 276 |
11 | Maltose and maltodextrin utilization | 270 |
12 | Sialic acid metabolism | 257 |
13 | Methionine degradation | 253 |
14 | Ribosome LSU bacterial | 252 |
15 | Glycolysis and gluconeogenesis | 244 |
16 | De novo pyrimidine synthesis | 238 |
17 | High affinity phosphate transporter | 236 |
18 | ECF class transporter | 234 |
19 | Purine conversion | 222 |
20 | Threonine and homoserine biosynthesis | 220 |