Fig. 5

Characterization of “promoter-like” exons. a Exon inclusion levels in C-higher (yellow) and C-lower (blue) cell lines in “promoter-like” and non “promoter-like” exons. b Transcription factors binding enrichment significance in C-higher over C-lower cell lines. Bonferroni corrected –log10(p-value) of the enrichment is represented for all the transcription factors tested. All the transcription factors had higher signal in C-higher (orange). No transcription factor was found enriched on C-lower cell lines in “promoter-like” exon, thus there is no blue dot represented on the graph. Solid colors represents significant enrichments (p < 0.05) (c-d) DNase I sensitivity and RNA polymerase II signals in promoter-like exons in C-higher and C-lower cell lines. Signals are represented for regulated (AS) and flanking non-regulated (notAS) exons. For input relative to panel (d) see Additional file 1: Figure S11