Fig. 2

Temporal analysis of both DNA methylation and gene expression at identified candidate genes. a Non-CGI mDMR genes undergoing developmental loss of methylation. b 3′ CGI mDMR genes undergoing developmental gain of methylation. The suckling period is highlighted in gray. For each gene, exon–intron structure (including isoforms) and CpG map are shown on the top. Thin blue bars represent the 5′ or 3′ UTRs and thick blue boxes represent coding exons. Each vertical line represents a CpG site and green bars indicate CGIs. Red dotted boxes indicate the regions analyzed for CpG methylation. The gene expression is relative to β-actin. Error bars represent standard error of the mean of three to five biological replicates