Fig. 2
From: Analysis methods for studying the 3D architecture of the genome
Impact of normalization on Hi-C contact maps. a, b Hi-C contact maps of chromosome 8 from the schizont stage of the parasite Plasmodium falciparum [16] at 10 kb resolution before and after normalization. Blue dashed lines represent the centromere location. c, d Density scatter plots of counts before (x-axis) and after (y-axis) normalization of Hi-C data from the human cell line IMR90 [15] at two different resolutions. Correlation values are computed using all intra-chromosomal contacts within human chromosome 8. Only a subset of points are shown for visualization purposes