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Fig. 5 | Genome Biology

Fig. 5

From: Comparative analyses of CTCF and BORIS occupancies uncover two distinct classes of CTCF binding genomic regions

Fig. 5

Genomic profiling of CTCF and BORIS occupancy in mouse germ cells. a Overlapping of CTCF (red) and BORIS (blue) genomic occupancy in mouse round spermatids. b Histogram indicates the percentage of conserved mouse CTCF and BORIS bound regions in the human genome. c Average tag density of CTCF (red) and BORIS (blue) occupancy in K562 cells across the conserved mouse binding regions from (b). d Gene tracks of CTCF and BORIS occupancy at the Tsp50/TSP50 (Prss50/PRSS50) gene in mouse (round spermatids) and human (K562) cells. e Average tag density (tags/10 million) of RNAPII, H3K4me3, and H3K27ac mapped by ChIP-seq in mouse testis (ENCODE data) across BORIS-only (blue), CTCF-only (red) and CTCF&BORIS (purple) bound regions mapped in mouse round spermatids. The data were normalized to the number of mapped reads and binding regions

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Genome Biology

ISSN: 1474-760X

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