Fig. 2
From: Genome-wide mapping of promoter-anchored interactions with close to single-enhancer resolution
Expression of HiCap-identified distal regions and their correlations with target gene expression. a Fraction of HiCap distal regions with expression above 0.1 or 1 RPKM compared with random regions sampled within the same distances from promoters as observed interactions. b Boxplot comparing the expression of genes connected to either highly expressed (>10 RPKM) or non-expressed (≤0.3 RPKM) distal regions; number of genes is given in parentheses. c Spearman correlation of the expression of HiCap-mapped distal regions and their closest HiCap connected target genes. d Spearman correlation of the expression of HiCap-mapped distal regions and the closest gene without HiCap interaction. e Spearman correlation of expression of HiCap distal regions and non-closest HiCap connected target genes. f Spearman correlation of expression levels of HiCap distal regions and the expression of randomly connected non-closest genes on the same chromosome. When multiple distal regions are connected to the same gene, the RPKM sum was used for analyses in (b–f)