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Fig. 1 | Genome Biology

Fig. 1

From: Quantitative detection of rare interphase chromosome breaks and translocations by high-throughput imaging

Fig. 1

hiBA-FISH outline. a hiBA-FISH pipeline. The green, red and blue dots represent FISH signals in fixed interphase cell nuclei. DAPI 4',6-diamidino-2-phenylindole, FISH fluorescence in situ hybridization, HTI high-throughput imaging, IR ionizing radiation, Pos. ctrl. positive control. b Outline of hiBA-FISH event definitions based on the thresholding of relative Euclidean distances of FISH signals in different colors. R-G min and R-FR min indicate the per Red signal minimum Red/Green and Red/FarRed distances, respectively. c Schematic representation of the size and location of the chromosome breakpoint regions recognized by the two different hiBA-FISH probe sets used in this study. Bcr breakpoint cluster region

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Genome Biology

ISSN: 1474-760X

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