Fig. 4
Genomic linkage disequilibrium (LD) in the MM population. The insert bottom right shows chromosome specific LD decay in the MM population with colors according to legend. Mean r 2 (y axis) is averaged in subsequent windows ad plotted on physical distance (x axis). LD is generally low and halves within 1 to 4 Mb (vertical dashed lines) suggesting high mapping resolution. Mean LD along chromosomes is plotted in the bigger panel. Each marker is considered separately, averaging for each the pairwise r 2 with all surrounding markers within ±1 Mb. Individual markers’ r 2 are then averaged in sliding windows of size 100 markers. Black arrows point centromeres. LD is generally higher in centromeric regions, but regions of higher LD are also present elsewhere (see Discussion in text)