Fig. 1

Drosophila Imp is present in cytoplasmic RNPs. a Protein domain architecture of Drosophila Imp and homologous vertebrate IMPs. The four KH domains are conserved whereas the glutamine (Q)-rich region and the two RNA recognition motifs (RRM) are structural features present in arthropods and chordates, respectively. b Immunocytochemistry of S2 cell with DAPI staining (blue), anti-Imp antibody (red) and phalloidin (green). c Correlation between the enrichment of immunoprecipitated transcripts in Imp RNPs from two biological RNA-binding protein immunoprecipitation (RIP)-seq replicates. The scatter plot shows the natural logarithm of RIP enrichment values per nucleotide in the whole transcript for each RIP-seq replicate. d Venn diagram of the 200 most enriched transcripts in Imp RNPs from two biological RIP-seq replicates