Table 1 Recent technological developments in epigenetics reported at the joint meetings
From: DNA methylation and epigenomics: new technologies and emerging concepts
Technique | Description | Speaker |
|---|---|---|
Single-cell DNA methylation | NA | Wolf Reik (Babraham Institute, UK) |
Single-cell Hi-C | NA | Peter Fraser (Babraham Institute, UK) |
Ligation-free Hi-C | Ligation-free assay for genome-wide chromatin interactions | Robert Beagrie (MRC Clinical Sciences Centre, UK) |
NOMe-seq | Assay developed in combination with ChIP-seq to analyze cancer in patients treated with DNMT inhibitors | Peter Jones (Van Andel Research Institute, USA) |
RAP | Method to identify genome-wide localization of a lncRNA | Mitchell Guttman (California Institute of Technology, USA) |
RAP-MS | Method to identify lncRNA-protein interactions | Mitchell Guttman |
SNP-FISH | Technique developed by Arjun Raj and colleagues to enable allele-specific expression analysis of single cells, or small groups of cells | Marisa Bartolomei (University of Pennsylvania Perelman School of Medicine, USA) |
HaploSeq | Haplotype reconstruction sequencing. In situ ligation to reconstruct long haplotype blocks | Bing Ren (University of California, San Diego, USA) |
NET-seq | Approach that exploits the extraordinary stability of the DNA-RNA-RNA polymerase ternary complex to capture nascent transcripts directly from live cells | L. Stirling Churchman (Harvard Medical School, USA) |
Methylation analysis software for the DRAGEN Bio-IT processor | Software used to carry out methylation analysis of a genome in 17Â minutes | Joseph Ecker (HHMI/The Salk Institute for Biological Studies, USA) |