Figure 4

Enrichment of PUM and BRAT motifs among associated mRNAs. (A) AUROC plots showing how well the PUM motif determined from our RIP-Chip data distinguishes the following sets from co-expressed non-targets: BRAT and PUM co-targets, BRAT-only targets (BRAT not PUM targets), and PUM-only targets (PUM not BRAT targets). (B) AUROC plots showing how well the BRAT motif determined from our RIP-Chip data distinguishes the following sets from co-expressed non-targets: BRAT and PUM co-targets, BRAT-only targets (BRAT not PUM targets), and PUM-only targets (PUM not BRAT targets). (C) AUROC plots showing how well the presence of a BRAT motif alone (as determined from our RIP-Chip data), a PUM motif alone (as determined from our RIP-Chip data), either a BRAT or a PUM motif (Either motif), or both a BRAT and a PUM motif (Both motifs), distinguish the set of BRAT and PUM co-targets from co-expressed non-targets.