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Figure 3 | Genome Biology

Figure 3

From: Domain atrophy creates rare cases of functional partial protein domains

Figure 3

N-terminal end-bounded atrophy: Bacterial luciferase. (A) Monomer of the atrophied bacterial luciferase domain of Photobacterium phosphoreum non-fluorescent flavoprotein (PDB: 1FVP, light green) bound to ligand FMA (6-(3-tetradecanoic acid) flavine mononucleotide, orange). (B) Monomer of the Bacillus cereus reference structure (PDB: 2B81, light blue). (C) Homo-dimer complex of 1FVP. The exposed hydrophobic core due to domain atrophy is stabilised by the new dimer interface. (D) Homo-dimer complex of 2B81 showing dimerisation on the same side of the molecule.

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