Evaluating intra- and inter-individual variation in the human placental transcriptome

Table 3 GO and KEGG enriched pathways for pairwise union of DE genes

Category	KEGG term	Adjusted P value	GO category	Ontology	GO term	Adjusted P value
4514	Cell adhesion molecules (CAMs)	0.0046	GO:0032501	BP	Multicellular organismal process	6.64E-10
5144	Malaria	0.0059	GO:0044707	BP	Single-multicellular organism process	4.57E-09
4142	Lysosome	0.0059	GO:0006950	BP	Response to stress	5.06E-09
5143	African trypanosomiasis	0.0143	GO:0044699	BP	Single-organism process	1.27E-08
4512	ECM-receptor interaction	0.0238	GO:0044763	BP	Single-organism cellular process	9.29E-08
4145	Phagosome	0.0678	GO:0050896	BP	Response to stimulus	1.01E-07
380	Tryptophan metabolism	0.0751	GO:0004872	MF	Receptor activity	2.07E-06
5020	Prion diseases	0.0751	GO:0002376	BP	Immune system process	2.07E-06
4610	Complement and coagulation cascades	0.0751	GO:0007275	BP	Multicellular organismal development	2.07E-06
5416	Viral myocarditis	0.1024	GO:0032502	BP	Developmental process	2.34E-06
4640	Hematopoietic cell lineage	0.1366	GO:0007154	BP	Cell communication	5.70E-06
5414	Dilated cardiomyopathy	0.1513	GO:0023052	BP	Signaling	6.39E-06
5150	Staphylococcus aureus infection	0.1513	GO:0044700	BP	Single organism signaling	6.39E-06
590	Arachidonic acid metabolism	0.1513	GO:0048731	BP	System development	7.32E-06
480	Glutathione metabolism	0.1683	GO:0006955	BP	Immune response	7.32E-06

Enriched pathways for the pairwise union of all DE genes. Shown are the KEGG pathways and GO categories observed to be enriched when using the union of genes identified as DE (1,784 genes) in each pairwise comparison found in Table 2 ‘Permutation’. The table provides the category identifiers (in the case of GO the ontology: BP = biological process, CC = cellular component, MF = molecular function), the associated term or brief description, and the Benjamini-Hochberg adjusted P value.

ISSN: 1474-760X