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Figure 2 | Genome Biology

Figure 2

From: Average genome size estimation improves comparative metagenomics and sheds light on the functional ecology of the human microbiome

Figure 2

Comparison of MicrobeCensus to existing methods. (A,B) Performance of MicrobeCensus was compared with that of existing methods using 20 simulated metagenomes. Unsigned error is defined as: |AÄœS - AGS|/AGS. (A) MicrobeCensus versus GAAS at different levels of taxonomic exclusion. To simulate the presence of novel taxa, we held back reference sequences belonging to organisms from the same taxonomic group as organisms in the metagenome, which is indicated on the x-axis. 'None' indicates that no reference sequences were held back. Metagenomes were composed of 100-bp reads. (B) Estimation error for MicrobeCensus versus the method described by Raes et al. [9] for metagenomes of various read length. 'NA' indicates that AGS could not be estimated. (C) Speed (reads/second) of MicrobeCensus compared with existing methods on a simulated 150-bp library.

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