Skip to content


Open Access

Expression of multiple horizontally acquired genes is a hallmark of both vertebrate and invertebrate genomes

Contributed equally
Genome Biology201516:50

Received: 25 September 2014

Accepted: 4 February 2015

Published: 13 March 2015

Back to article

Archived Comments

  1. In HGT how have foreign sequences entered the human genome?

    23 March 2015

    Kevin Smith, Abertay University

    I suggest that the most likely route by which exogenous sequences have entered the human genome is via sperm-mediated gene transfer. I hypothesised about this possibility previously, if interested please see Smith K. The Role of Sperm-Mediated Gene Transfer in Genome Mutation and Evolution. Medical Hypotheses, 2002; 59(4): 433-437.



    Competing interests

    None declared

Authors’ Affiliations

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, UK
Department of Genetics, University of Cambridge, Cambridge, UK
Cambridge Systems Biology Centre, University of Cambridge, Cambridge, UK