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Table 1 Assessment of ChrY gene copy number among B6-ChrY consomic strains

From: Copy number variation in Y chromosome multicopy genes is linked to a paternal parent-of-origin effect on CNS autoimmune disease in female offspring

  Slx b Sly Ssty1 Ssty2 Srsy Rbmy Rbm31y
C57BL/6 J BACsa   126 85 221 197 30 2
C57BL/6 J 26 ± 1 128 ± 6 85 ± 4 238 ± 49 199 ± 13 30 ± 1 2 ± 0
B6-ChrYPWD 29 ± 2 150 ± 6 70 ± 4 375 ± 33 219 ± 17 29 ± 1 1 ± 0
B6-ChrYA/J 26 ± 1 136 ± 9 102 ± 4 287 ± 91 226 ± 7 31 ± 1 2 ± 0
B6-ChrY129 29 ± 2 155 ± 9 90 ± 5 620 ± 87 225 ± 21 26 ± 1 2 ± 0
B6-ChrYMA 26 ± 1 45 ± 2 510 ± 8 2381 ± 249 248 ± 18 8 ± 0 1 ± 0
B6-ChrYBUB 27 ± 2 19 ± 1 290 ± 25 1041 ± 158 143 ± 15 11 ± 0 1 ± 0
B6-ChrYST 24 ± 1 20 ± 1 272 ± 10 366 ± 49 154 ± 5 10 ± 1 1 ± 0
B6-ChrYLEWES 26 ± 1 24 ± 1 310 ± 39 87 ± 7 69 ± 5 9 ± 1 1 ± 0
B6-ChrYMET 28 ± 2 70 ± 5 91 ± 3 183 ± 16 91 ± 9 30 ± 1 2 ± 0
B6-ChrYAKR 27 ± 1 36 ± 4 340 ± 64 237 ± 9 118 ± 13 7 ± 0 1 ± 0
B6-ChrYSWR 26 ± 1 23 ± 1 259 ± 8 580 ± 54 174 ± 10 11 ± 1 1 ± 0
B6-ChrYWSB 27 ± 1 41 ± 4 411 ± 59 787 ± 93 130 ± 14 7 ± 0 1 ± 0
B6-ChrYSJL 27 ± 1 16 ± 1 350 ± 56 1289 ± 194 171 ± 20 11 ± 0 1 ± 0
B6-ChrYRF 28 ± 1 33 ± 1 407 ± 18 1503 ± 101 134 ± 10 9 ± 1 1 ± 0
  1. aCopy number of ChrY genes determined by sequencing from C57BL/6 J BAC libraries [29]. This number was assigned to a B6 calibrator sample and used to calculate CNV for the ChrY consomic strains.
  2. bEstimated copy number of 25 was assigned to a B6 calibrator sample to calculate CNV in Slx among female offspring of B6-ChrY consomic strains [29].
  3. Numbers represent the mean copy number ± standard error of the mean rounded to the nearest integer. n = 3 to 5 mice per strain.