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Table 1 Clinical and anthropometric data for individuals in the study

From: An analysis of DNA methylation in human adipose tissue reveals differential modification of obesity genes before and after gastric bypass and weight loss

Trait Before weight loss After weight loss T statistic P value
Age (years) 44 (+/− 10) 45 (+/− 10) −7.64 1.16 × 10−6
Weight (kg) 123.9 (+/− 33.32) 76.2 (+/− 15.4) 8.31 4.42 × 10−7
BMI (kg/m2) 47.6 (+/− 11.3) 29.3 (+/− 5.5) 9.10 1.48 × 10−7
Glucose (mmol/L) 5.5 (+/− 1.2) 4.6 (+/− 0.6) 2.35 0.017
Insulin (pmol/L) 176.2 (+/− 168.1) 33.4 (+/− 19.3) 3.04 0.006
HbA1c 6.0 (+/− 0.6) 5.5 (+/− 0.5) 2.42 0.018
Triglycerides (mmol/L) 1.6 (+/− 0.7) 1.0 (+/− 0.3) 3.00 0.005
Total cholesterol (mmol/L) 5.3 (+/− 0.8) 4.6 (+/− 0.6) 4.23 4.48 × 10−4
HDL (mmol/L) 1.4 (+/− 0.4) 1.8 (+/− 0.9) −1.46 0.083
LDL (mmol/L) 3.2 (+/− 1.1) 2.6 (+/− 0.6) 2.71 0.009
Systolic blood pressure (mmHg) 135 (+/− 18) 115 (+/− 9) 3.37 0.003
Diastolic blood pressure (mmHg) 78 (+/− 13) 73 (+/− 9) 1.67 0.061
Time (months)   17.6 (+/− 6.9)   
  1. Data are expressed as means +/− standard deviation, based on a paired t-test and one-tailed P value (given that gastric bypass is known to result in a marked reduction in weight and metabolic risk).