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Table 1 Clinical and anthropometric data for individuals in the study

From: An analysis of DNA methylation in human adipose tissue reveals differential modification of obesity genes before and after gastric bypass and weight loss

Trait

Before weight loss

After weight loss

T statistic

P value

Age (years)

44 (+/− 10)

45 (+/− 10)

−7.64

1.16 × 10−6

Weight (kg)

123.9 (+/− 33.32)

76.2 (+/− 15.4)

8.31

4.42 × 10−7

BMI (kg/m2)

47.6 (+/− 11.3)

29.3 (+/− 5.5)

9.10

1.48 × 10−7

Glucose (mmol/L)

5.5 (+/− 1.2)

4.6 (+/− 0.6)

2.35

0.017

Insulin (pmol/L)

176.2 (+/− 168.1)

33.4 (+/− 19.3)

3.04

0.006

HbA1c

6.0 (+/− 0.6)

5.5 (+/− 0.5)

2.42

0.018

Triglycerides (mmol/L)

1.6 (+/− 0.7)

1.0 (+/− 0.3)

3.00

0.005

Total cholesterol (mmol/L)

5.3 (+/− 0.8)

4.6 (+/− 0.6)

4.23

4.48 × 10−4

HDL (mmol/L)

1.4 (+/− 0.4)

1.8 (+/− 0.9)

−1.46

0.083

LDL (mmol/L)

3.2 (+/− 1.1)

2.6 (+/− 0.6)

2.71

0.009

Systolic blood pressure (mmHg)

135 (+/− 18)

115 (+/− 9)

3.37

0.003

Diastolic blood pressure (mmHg)

78 (+/− 13)

73 (+/− 9)

1.67

0.061

Time (months)

 

17.6 (+/− 6.9)

  
  1. Data are expressed as means +/− standard deviation, based on a paired t-test and one-tailed P value (given that gastric bypass is known to result in a marked reduction in weight and metabolic risk).