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Table 2 Measured factors that influenced the temporal variability of the human microbiome

From: Temporal variability is a personalized feature of the human microbiome

  Parameter estimate Sum of squares F statistic P value BIC R 2
Forehead - unweighted       
Antibiotic use 0.015 0.010 8.76 0.004 -262.21 0.175
University 0.119 0.006 5.41 0.023 -263.38  
Forehead - weighted       
Median Shannon 0.038 0.090 32.2 3.61 e -7 -190.67 0.580
Gender 0.023 0.027 9.54 0.003 -193.54  
Roommates (n) 0.039 0.016 5.70 0.02 -196.16  
Gut - unweighted       
Median Shannon 0.063 0.081 73.24 4.3 e -12 -240.90 0.570
Over-the-counter acne product 0.014 0.013 11.18 0.001 -249.97  
University 0.014 0.007 6.64 0.012 -254.34  
Gut - weighted       
Median Shannon 0.107 0.238 20.64 2.61 e -5 -85.83 0.319
Over-the-counter acne product 0.034 0.065 5.65 0.021 -90.53  
University 0.028 0.047 4.08 0.047 -90.55  
Palm - unweighted       
Exercise frequency 0.033 0.022 15.74 2.00 e -4 -188.6 0.310
Lives with dogs 0.014 0.010 7.18 0.009 -189.9  
Roommates (n) 0.016 0.008 5.77 0.019 -191.8  
Palm - weighted       
Antibiotic use 0.026 0.024 4.97 0.029 -129.8 0.080
Tongue - unweighted       
Antibiotic use 0.018 0.015 7.75 0.007 -217.82 0.215
Median Shannon 0.038 0.010 5.5 0.022 -220.12  
Tongue - weighted       
No good model       
  1. Generalized linear models (GLMs) were used to determine which of the measured factors or combination of factors best predicted variability in microbiome membership (unweighted UniFrac) and structure (weighted UniFrac). Unweighted UniFrac distances are a metric of the phylogenetic dissimilarity of samples through time. Weighted UniFrac distances weight dissimilarity both as a function of the phylogenetic dissimilarity and the relative abundance of taxa (such that two samples with the same phylogenetic dissimilarity are considered more different if one is dominated by a particular taxon).
  2. BIC = Bayesian Information Criterion.