Figure 4
From: Characterizing heterogeneity in leukemic cells using single-cell gene expression analysis
Experimental validation of the functional difference between the two leukemic cell subtypes. (A) Snapshot of a colony-forming assay of CD24- leukemic cells on day 7. (B) Snapshot of a colony-forming assay of CD24+ leukemic cells on day 7. (C) Number of spread-type colonies of different leukemic cell subpopulations. (D) Number of sphere-type colonies of different leukemic cell subpopulations. (E) Total number of cells after one-week culture in methylcellulose supplemented with IL3, IL6, IL7 and stem cell factor. The error bars represent standard deviation.