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Figure 2 | Genome Biology

Figure 2

From: Mapping and manipulating the Mycobacterium tuberculosis transcriptome using a transcription factor overexpression-derived regulatory network

Figure 2

Features of the TFOE dataset. (A) TFOE-induced transcriptional changes vary widely in size and composition. Each of the 183 TFOE regulons (genes differentially expressed (DE) two-fold with a FDR adjusted P value <0.01) is represented as a single bar indicating the total number of genes DE. Each column representing a TF was further characterized as either entirely or primarily an inducer (red), repressor (blue), or bifunctional regulator (yellow). (B) Ectopic induction inversely correlates with baseline expression level. The level of induction for each TF is strongly correlated with the uninduced expression level, however neither of those variables is correlated with the size of the regulon (C).

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Genome Biology

ISSN: 1474-760X

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